Shashikant Kulkarni, MS, PhD, FACMG




Molecular and Human Genetics
Baylor College of Medicine
Houston, TX, US

Co-Vice Chair of Research
Molecular and Human Genetics
Baylor College of Medicine

Chief Scientific Officer
Baylor Genetics

Senior Vice President of Operations
Baylor Genetics

Co-Program Director
American Board of Medical Genetics and Genomics (ABMGG) Laboratory Genetics
Fellowship, Molecular and Human Genetics
Baylor College of Medicine
Houston, Texas


PhD from All India Institute of Medical Sciences
New Delhi, India
Medical Genetics

Fellowship at Hammersmith Hospital, Imperial College
London, United Kingdom

Postdoctoral Training at Brigham and Women's Hospital, Harvard Medical School
Boston, Massachusetts, United States


Clinical Cytogenetics
American Board of Medical Genetics

Clinical Molecular Genetics
#Board Eligible
American Board of Medical Genetics


• Griffith M, Griffith OL, Krysiak K, (...), Kulkarni S, DiPersio JF, Mardis E, Wilson RK, Ley TJ. "Comprehensive genomic analysis reveals FLT3 activation and a therapeutic strategy for a patient with relapsed adult B-lymphoblastic leukemia." Exp Hematol. 2016 July;44:603-613. Pubmed PMID: 27181063
• Griffith M, Miller C, Griffith O, (...), Kulkarni S, Cordes M, Fronick C, Fulton R, Maher C, Ding L, Klco J, Mardis E, Ley T, Wilson R. "Optimizing Cancer Genome Sequencing and Analysis." Cell Systems. 2015 September 23;1:210-323. Pubmed PMID: 26645048
• Klco J, Miller C, Griffith M, (...), Kulkarni S, Ozenberger B, Welch J, Walter M, Graubert T, Westervelt, P, Radich J, Link D, Mardis E, DiPersio, J, Wilson R, Ley T.. "Association Between Mutation Clearance After Induction Therapy and Outcomes in Acute Myeloid Leukemia." JAMA. 2015 August 15;314:811-22. Pubmed PMID: 26305651
• Gargis AS, Kalman L, Bick DP, Da Silva C, Dimmock DP, Funke BH, Gowrisankar S, Hedge MR, Kulkarni S, et. al. "Good laboratory practive for clinical next-generation sequencing informatics pipelines.Nat Biotechnol. 2015 July;33:689-93. Pubmed PMID: 26154004
• Ungewickell A, Bhanduri A, Rios E, Reuter J, Lee C, Mah A, Zehnder A, Ohgami R, Kulkarni S, Armstorng R, Weng W, Gratzinger D, Tavallaee M, Rook A, Snyder M, Kim Y, Khavari P. "Genomic analysis of mycosis fungoides and Sézary syndrome identifies recurrent alterations in TNFR2.Nat Genet. 2015 September;47:1056-60. Pubmed PMID: 26258847
• Lyon E, Cockerill FR 3rd, Bale SJ, Beadling C, Bry L, Hagenkord J, Kulkarni S, Press R, Palomaki GE. "Next generation sequencing in clinical diagnostics: experiences of early adopters." Clin Chem. 2015 January;61:41-9. Pubmed PMID: 25421800
• Perrino CM, Hucthagowder V, Evenson M, Kulkarni S, Humphrey PA. "Genetic alterations in renal cell carcinoma with rhabdoid differentiation." Hum Pathol. 2015 January;46:9-16. Pubmed PMID: 25439741
• Hagemann IS, Devarakonda S, Lockwood CM, Spencer DH, Guebert K, Bredemeyer AJ, Al-Kateb H, Nguyen TT, Duncavage EJ, Cottrell CE, Kulkarni S, et. al.. "Clinical next-generation sequencing in patients with non-small cell lung cancer." Cancer. 2015 February 15;121:631-9. Pubmed PMID: 25345567
• Welch JS, Ley TJ, Link DC, (...), Kulkarni S, Klco JM, Tomasson MH, Westervelt P, Walter MJ, Graubert TA, DiPersio JF, Ding L, Mardis ER, Wilson RK. "The origin and evolution of mutations in acute myeloid leukemia." Cell. 2012 July 20;150:264-78. Pubmed PMID: 22817890
• Ding L, Ley TJ, Larson DE, (...), Kulkarni S, Westervelt P, Walter MJ, Graubert TA, Mardis ER, Wilson RK, DiPersio JF. "Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing." Nature. 2012 January 11;481:506-10. Pubmed PMID: 22237025