Vernon R. Sutton, MD

ABMG Certified Clinical and Biochemical Geneticist



Molecular and Human Genetics
Baylor College of Medicine
Houston, TX, US

Medical Director
Biochemical Genetics Laboratory
Baylor Genetics

Medical Genetics Residency Program
Baylor College of Medicine

ABMGG Diagnostic Laboratory Training Programs
Baylor College of Medicine

Inborn Errors of Metabolism Service
Texas Children's Hospital


BA from Transylvania University, Kentucky
01/1988 - Lexington, KY, United States

MD from University Of Kentucky College Of Medicine
01/1992 - Lexington, KY, United States

Residency at Washington University Affiliate Hospitals
01/1996 - St. Louis, MO, United States

Clinical Fellowship at Baylor College Of Medicine
01/1999 - Houston, TX, United States
Medical Genetics


Clinical Genetics
American Board of Medical Genetics

Clinical Biochemical Genetics
American Board of Medical Genetics


• Osteogenesis imperfecta/brittle bone disease
• Achondroplasia
• Creatine transporter deficiency
• Aicardi syndrome


• Miller MJ, Kennedy AD, Eckhart AD, Burrage LC, Wulff JE, Miller LA, Milburn MV, Ryals JA, Beaudet AL, Sun Q, Sutton VR, Elsea SH. "Untargeted metabolomic analysis for the clinical screening of inborn errors of metabolism." J Inherit Metab Dis. 2015 April 15;38:1029-39. Pubmed PMID: 25875217
• Chong JX, Buckingham KJ, Jhangiani SN, Boehm C, Sobreira N,..., Sutton VR, Tabor HK, Leal SM, Gunel M, Mane S, Gibbs RA, Boerwinkle E, Hamosh A, Shendure J, Lupski JR, Lifton RP, Valle D, Nickerson DA; Centers for Mendelian Genomics, Bamshad MJ. "The Genetic Basis of Mendelian Phenotypes: Discoveries, Challenges, and Opportunities." Am J Hum Genet. 2015 August 6;97(2):199-215. Pubmed PMID: 26166479
• White J, Mazzeu JF, Hoischen A, Jhangiani SN, ..., Muzny DM, Sutton VR, Gibbs RA; Baylor-Hopkins Center for Mendelian Genomics, Lupski JR, Brunner HG, van Bon BW, Carvalho CM. "DVL1 frameshift mutations clustering in the penultimate exon cause autosomal-dominant Robinow syndrome." Am J Hum Genet. 2015 April 2;96:612-22. Pubmed PMID: 25817016
• Atwal PS, Donti TR, Cardon AL, Bacino CA, Sun Q, Emrick L, Reid Sutton V, Elsea SH. "Aromatic L-amino acid decarboxylase deficiency diagnosed by clinical metabolomic profiling of plasma." Mol Genet Metab. 2015 June;115:91-4. Pubmed PMID: 25956449
• Patel RM, Nagamani SC, Cuthbertson D, Campeau PM, Krischer JP, Shapiro JR, Steiner RD, Smith PA, Bober MB, Byers PH, Pepin M, Durigova M, Glorieux FH, Rauch F, Lee BH, Hart T, Sutton VR. "A cross-sectional multicenter study of osteogenesis imperfecta in North America - results from the linked clinical research centers." Clin Genet. 2015 February;87:133-40. Pubmed PMID: 24754836
• Sutton VR, van Bokhoven H. "TP63-Related Disorders." In: Pagon RA, Adam MP, Ardinger HH, Wallace S. 2015 August 6 Pubmed PMID: 20556892
• Wu N, Ming X, Xiao J, Wu Z, Chen X, Shinawi M, Shen Y,..., Sutton VR, Wang H, Ming Y, Kulkarni S, Zhong TP, Giampietro PF, Dunwoodie SL, Cheung SW, Zhang X, Jin L, Lupski JR, Qiu G, Zhang F. "TBX6 null variants and a common hypomorphic allele in congenital scoliosis." N Engl J Med. 2015 January 22;372(4):341-50. Pubmed PMID: 25564734
• Sutton VR, Van den Veyver IB. "Aicardi Syndrome." In: Pagon RA, Adam MP, Ardinger HH, Wallace S. 2014 November 6 Pubmed PMID: 20301555
• Miller MJ, Soler-Alfonso CR, Grund JE, Fang P, Sun Q, Elsea SH, Sutton VR. "Improved standards for prenatal diagnosis of citrullinemia." Mol Genet Metab. 2014 July;112(3):205-9. Pubmed PMID: 24889030
• Chandler RJ, Tarasenko TN, Cusmano-Ozog K, Sun Q, Sutton VR, Venditti CP, McGuire PJ. "Liver-directed adeno-associated virus serotype 8 gene transfer rescues a lethal murine model of citrullinemia type 1." Gene Ther. 2013 December;20(12):1188-91. Pubmed PMID: 24131980
• Sutton VR, Van den Veyver IB. "Focal Dermal Hypoplasia." In: Pagon RA, Adam MP, Ardinger HH, Wallace S. 2013 April 11 Pubmed PMID: 20301712
• Douglas G, Axelrad ME, Brandt ML, Crabtree E, Dietrich JE, French S, Gunn S, Karaviti L, Lopez ME, Macias CG, McCullough LB, Suresh D, Austin E, Reid Sutton V. "Guidelines for evaluating and managing children born with disorders of sexual development.." Pediatr Ann.. 2012;41(4):e1-7. Pubmed PMID: 22494213
• Sutton VR, Chapman KA, Gropman AL, Macleod E, Stagni K, Summar ML, Ueda K, Ah Mew N, Franks J, Island E, Matern D, Peña L, Smith B, Urv T, Venditti C, Chakarapani A. "Chronic management and health supervision of individuals with propionic acidemia.." Mol. Genet. Metab.. 2012 January;105(1):26-33. Pubmed PMID: 21963082
• Fernandes PH, Wen S, Sutton VR, Ward PA, Van den Veyver IB, Fang P. "PORCN Mutations and Variants Identified in Patients with Focal Dermal Hypoplasia Through Diagnostic Gene Sequencing.." Genet Test Mol Biomarkers. 2010 October;14(5):709-13. Pubmed PMID: 20854095
• Sutton VR, Plunkett K, Dang DX, Lewis RA, Bree AF, Bacino CA. "Craniofacial and anthropometric phenotype in ankyloblepharon-ectodermal defects-cleft lip/palate syndrome (Hay-Wells syndrome) in a cohort of 17 patients.." Am. J. Med. Genet. A. 2009 September;149(9):1916-21. Pubmed PMID: 19676059
• Eble TN, Sutton VR, Sangi-Haghpeykar H, Wang X, Jin W, Lewis RA, Fang P, Van den Veyver IB. "Non-random X chromosome inactivation in Aicardi syndrome.." Hum. Genet.. 2009 March;125(2):211-6. Pubmed PMID: 19116729
• Wang X, Sutton VR, Eble TN, Lewis RA, Gunaratne P, Patel A, Van den Veyver IB. "A genome-wide screen for copy number alterations in Aicardi syndrome.." Am. J. Med. Genet. A. 2009 October;149(10):2113-21. Pubmed PMID: 19760649
• Hopkins B, Sutton VR, Lewis RA, Van den Veyver I, Clark G. "Neuroimaging aspects of Aicardi syndrome.." Am. J. Med. Genet. A. 2008 November 15;146(22):2871-8. Pubmed PMID: 18925666
• Glasmacher MA, Sutton VR, Hopkins B, Eble T, Lewis RA, Park Parsons D, Van den Veyver IB. "Phenotype and management of Aicardi syndrome: new findings from a survey of 69 children.." J. Child Neurol.. 2007 February;22(2):176-84. Pubmed PMID: 17621479
• Cheung SW, Shaw CA, Scott DA, Patel A, Sahoo T, Bacino CA, Pursley A, Li J, Erickson R, Gropman AL, Miller DT, Seashore MR, Summers AM, Stankiewicz P, Chinault AC, Lupski JR, Beaudet AL, Sutton VR. "Microarray-based CGH detects chromosomal mosaicism not revealed by conventional cytogenetics.." Am. J. Med. Genet. A. 2007 August 1;143(15):1679-86. Pubmed PMID: 17607705
• Wang X*, Sutton VR*, Peraza O, Yu Z, Rosetta R, Kou YC, Eble TN, Patel A, Thaller C, Fang P, Van den Veyver IB. "Mutations in X-linked PORCN, a putative regulator of Wnt signaling, cause focal dermal hypoplasia.." Nat Genet.. 2007;39(7):836-8. Pubmed PMID: 17546030


American Society of Human Genetics

American College of Medical Genetics
Member of Professional Practice and Guidelines Committee

International Skeletal Dysplasia Society

Society of Inherited Metabolic Diseases