Carlos A. Bacino, MD




ABMG Certified Clinical,
Cytogenetics and Molecular Geneticist


POSITIONS

Professor
Molecular and Human Genetics
Baylor College of Medicine
Houston, TX, US

Vice Chair of Clinical Affairs
Molecular and Human Genetics
Baylor College of Medicine

Chief
Genetics Service
Texas Children's Hospital
Houston, Texas, United States

Director
Pediatrics Genetics Clinic
Texas Children's Hospital
Houston, Texas, United States

Medical Director
Cytogenetics Laboratory
Baylor Genetics
Houston, Texas, United States

EDUCATION

MD from Fac. De Ciencias Med., U. De Buenos Aires
01/1981 - Buenos Aires, Argentina

Residency at Beth Israel Medical Center
01/1991 - New York, NY, United States

Clinical Fellowship at Cedars-Sinai Medical Center
01/1994 - Los Angeles, California, United States
Clinical Genetics and Cytogenetics

CERTIFICATIONS

Clinical Genetics
American Board of Medical Genetics

Clinical Cytogenetics
American Board of Medical Genetics

Clinical Molecular Genetics
American Board of Medical Genetics

PROFESSIONAL INTERESTS

• Clinical studies in patients with imprinting disorders (Angelman Syndrome), skeletal dysplasias, and genomic disorders

SELECTED PUBLICATIONS

• Brunetti-Pierri N, Torrado M, Fernandez Mdel C, Tello AM, Arberas CL, Cardinale A, Piccolo P, Bacino CA. "Terminal osseous dysplasia with pigmentary defects (TODPD) due to a recurrent filamin A (FLNA) mutation." Mol. Genet. Genomic Med.. 2014 November;2:467-71. Pubmed PMID: 25614868
• Bacino CA, Hecht JT. "Etiopathogenesis of equinovarus foot malformations." Eur J Med Genet. 2014 August;57:473-9. Pubmed PMID: 24932901
• Bornstein E, Bacino CA, Maliszewski K, Delaney K, Moyal R, Divon MY. "Isolated fetal macrodactyly: phenotypic and genetic disparities in mosaic overgrowth syndrome." J Ultrasound Med. 2014 July;33(7):1305-7. Pubmed PMID: 24958419
• Bacino CA, Dhar SU, Brunetti-Pierri N, Lee B, Bonnen PE. "WDR35 mutation in siblings with Sensenbrenner syndrome: A ciliopathy with variable phenotype." Am J Med Genet A. 2012 November;158(11):2917-24. Pubmed PMID: 22987818
• Burrage LC, Person RE, Flores A, Villanos MT, Bi W, Wiszniewska J, Bacino CA. "De novo interstitial duplication of 15q11.2-q13.1 with complex maternal uniparental trisomy for the 15q11-q13 region in a patient with Prader-Willi syndrome." Am J Med Genet A. 2012 October;158(10):2557-63. Pubmed PMID: 22903639
• Bacino CA, Arriola LA, Wiszniewska J, Bonnen PE. "WDR62 missense mutation in a consanguineous family with primary microcephaly." Am J Med Genet A. 2012 March;158(3):622-5. Pubmed PMID: 22308068
• Berg JS, Potocki L, Bacino CA. "Common recurrent microduplication syndromes: diagnosis and management in clinical practice." Am J Med Genet A. 2010 May;152(5):1066-78. Pubmed PMID: 20425813
• Tompson SW, Bacino CA, Safina NP, Bober MB, Proud VK, Funari T, Wangler MF, Nevarez L, Ala-Kokko L, Wilcox WR, Eyre DR, Krakow D, Cohn DH. "Fibrochondrogenesis results from mutations in the COL11A1 type XI collagen gene." Am J Hum Genet. 2010 November 12;87(5):708-12. Pubmed PMID: 21035103
• Brunetti-Pierri N, Lachman R, Lee K, Leal SM, Piccolo P, Van Den Veyver IB, Bacino CA. "Terminal osseous dysplasia with pigmentary defects (TODPD): Follow-up of the first reported family, characterization of the radiological phenotype, and refinement of the linkage region." Am. J. Med. Genet. A. 2010 July;152(7):1825-31. Pubmed PMID: 20583181
• Sutton VR, Plunkett K, Dang DX, Lewis RA, Bree AF, Bacino CA. "Craniofacial and anthropometric phenotype in ankyloblepharon-ectodermal defects-cleft lip/palate syndrome (Hay-Wells syndrome) in a cohort of 17 patients." Am J Med Genet A. 2009 September;149(9):1916-21. Pubmed PMID: 19676059
• Yatsenko SA, del Valle Torrado M, Fernandes PH, Wiszniewska J, Gallego M, Herrera J, Bacino CA. "Molecular characterization of a balanced rearrangement of chromosome 12 in two siblings with Noonan syndrome." Am J Med Genet A. 2009 December;149(12):2723-30. Pubmed PMID: 19938085
• Brunetti-Pierri N, Del Gaudio D, Peters H, Justino H, Ott CE, Mundlos S, Bacino CA. "Robinow syndrome: phenotypic variability in a family with a novel intragenic ROR2 mutation." Am J Med Genet A. 2008 November 1;146(21):2804-9. Pubmed PMID: 18831060
• Kang SH, Scheffer A, Ou Z, Li J, Scaglia F, Belmont J, Lalani SR, Roeder E, Enciso V, Braddock S, Buchholz J, Vacha S, Chinault AC, Cheung SW, Bacino CA. "Identification of proximal 1p36 deletions using array-CGH: a possible new syndrome." Clin Genet. 2007;72(4):329-38.
• Zhang W, Amir R, Stockton DW, Van Den Veyver IB, Bacino CA, Zoghbi HY. "Terminal osseous dysplasia with pigmentary defects maps to human chromosome Xq27.3-xqter." Am J Hum Genet. 2000 April;66(4):1461-4. Pubmed PMID: 10739772

MEMBERSHIPS

American Society of Human Genetics
Member

American College of Medical Genetics
Member

Society for Pediatric Research
Member

Tetratology Society
Member